规格: | 98% |
分子量: | 849.9 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
Background:
10-acetyl Docetaxel is a derivative of paclitaxel and an inhibitor of microtubule depolymerization.1It inhibits calcium-induced depolymerization of calf brain microtubule protein (MTP) in a cell-free assay when used at 20 µM. 10-acetyl Docetaxel is cytotoxic to J774.2 cells (EC50= 0.05 µM).
1.Swindell, C.S., Heerding, J.M., Krauss, N.E., et al.Characterization of the taxol structure-activity profile for the locus of the A-ring side chainBioorg. Med. Chem. Lett.4(12)1531-1536(1994)