Butin是从黄檀的心材中分离出的主要的一种生物活性黄酮类化合物，具有很强的抗氧化、抗血小板和抗炎活性。在大鼠中，Butin能显著减轻心肌梗死现象，改善心脏功能，预防糖尿病引起的心脏氧化损伤。
货号:ajcx31720
CAS:21913-99-5
分子式:C15H12O5
分子量：272.25
溶解度:DMSO: 41.67 mg/mL (153.06 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat[1][2].

[1]. Duan J, et al. Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway. Sci Rep. 2017 Jan 27;7:41491. [2]. Li P, et al. Butin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage by Anti Inflammatory Pathway. Transl Neurosci. 2018 May 8;9:7-12.