Gln-AMS(TFA)是Ia类型的氨酰基-tRNA合成酶(AARS)抑制剂。Gln-AMS抑制谷氨酰胺酰-tRNA合成酶的Ki值为1.32µM。
货号:ajcx13388
CAS:N/A
分子式:C17H23F3N8O10S
分子量：588.47
溶解度:DMSO : ≥ 100 mg/mL (169.93 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM.

Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor[2].

[1]. Rath VL, et al. How glutaminyl-tRNA synthetase selects glutamine. Structure. 1998 Apr 15;6(4):439-49. [2]. Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.