FLT3-IN-6 是一种有效、选择性的 FLT3-ITD (FLT3 突变体) 抑制剂，IC50 值为 1.336 nM。
货号:ajcx13904
CAS:N/A
分子式:C23H25N5O3
分子量：419.48
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM[1]. IC50: 1.336 nM (FLT3-ITD)[1]

[1]. Heng H, et al. Combining structure- and property-based optimization to identify selective FLT3-ITD inhibitors with good antitumor efficacy in AML cell inoculated mouse xenograft model. Eur J Med Chem. 2019 Aug 15;176:248-267.