Z-VA-DL-D(OMe)-FMK (Z-VAD-FMK) is a pan-caspase inhibitor.
货号:ajcx17468
CAS:N/A
分子式:C22H30FN3O7 • XCF3COOH
分子量：467.5
溶解度:DMSO: 1 mg/ml,Formic Acid: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Z-VA-DL-D(OMe)-FMK (Z-VAD-FMK) is a pan-caspase inhibitor. It inhibits anti-Fas antibody-induced cleavage of caspase-3 and PARP in Jurkat T lymphocytes when used at a concentration of 0.5 μM. Z-VAD-FMK (50 μM) inhibits cell death induced by TNF-α and cycloheximide co-application in HeLa cells. It also inhibits radiation-induced increases in the number of TUNEL-positive neurons in the rat hypoglossal nucleus when administered intracerebroventricularly at a dose of 2 μg per animal.