您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Adenosine 3&rsquo-monophosphate(sodium salt hydrate)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Adenosine 3&rsquo-monophosphate(sodium salt hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Adenosine 3&rsquo-monophosphate(sodium salt hydrate)图片
规格:98%
分子量:347.2
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍
A nucleotide
货号:ajcx24992
CAS:N/A
分子式:C10H14N5O7P·XNa [XH2O]
分子量:347.2
溶解度:PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .


1.Rao, F., Yaning, Q., Murugan, E., et al.20,30-cAMP hydrolysis bymetal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screeningBiochem. Bioph. Res. Commun.398(3)500-505(2010) 2.Jackson, E.K., Gillespie, D.G., and Dubey, R.K.2’-AMP and 3’-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptorsJ. Pharmacol. Exp. Ther.337(2)444-450(2011)