An antiviral nucleoside analog
货号:ajcx25222
CAS:3416-05-5
分子式:C10H14N2O4
分子量：226.2
溶解度:DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3′-deoxy Thymidine is a nucleoside analog of thymidine that has antiviral activity.¹It inhibits HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC₅₀= 0.17 µM).²3′-deoxy Thymidine (1, 3, 10, or 30 µM) reduces viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).¹

1.Waqar, M.A., Evans, M.J., Manly, K.F., et al.Effects of 2’,3’-dideoxynucleosides on mammalian cells and virusesJ. Cell. Physiol.121(2)402-408(1984) 2.Lin, T.-S., Schinazi, R.F., and Prusoff, W.H.Potent and selective in vitro activity of 3’-deoxythymidin-2’-ene (3’-deoxy-2’,3’-didehydrothymidine) against human immunodeficiency virusBiochem. Pharmacol.36(17)2713-2718(1987)