The levorotary enantiomer of medetomidine
货号:ajcx25984
CAS:190000-46-5
分子式:C13H16N2 • HCl
分子量：236.7
溶解度:DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Levomedetomidine is the levorotary enantiomer of the racemic α₂-adrenergic receptor (α₂-AR) agonist medetomidine.¹Unlike medetomidine or the dextrorotary enantiomer dexmedetomidine , levomedetomidine does not induce sedation or analgesia when administered alone in dogs.²However, levomedetomidine does reduce the level of dexmedetomidine-induced sedation in dogs. Formulations containing levomedetomidine have been used as anesthetics.

1.Kim, S.M., Lee, B., An, H.J., et al.Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during agingOncotarget8(28)46273-46285(2017) 2.Kuusela, E., Vainio, O., Kaistinen, A., et al.Sedative, analgesic, and cardiovascular effects of levomedetomidine alone and in combination with dexmedetomidine in dogsAm. J. Vet. Res.62(4)616-621(2001)