TP-004 是一种强效、可逆的 MetAP2 抑制剂，其 IC50 值为 6 nM。
货号:ajcx29742
CAS:1454299-21-8
分子式:C17H16F3N5O
分子量：363.34
溶解度:DMSO: 250 mg/mL (688.06 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM[1].

[1]. Cheruvallath, Z., et al. Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1. Bioorganic & Medicinal Chemistry Letters, 26(12), 2774-2778.