BDP-13176是一种有效的fascin1抑制剂，Kd值为90nM，IC50值为240nM。BDP-13176具有成为抗转移剂的潜力。
货号:ajcx32108
CAS:2290660-61-4
分子式:C24H22Cl2N6O2
分子量：497.38
溶解度:DMSO: 125 mg/mL (251.32 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1].

BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity[1].

[1]. Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029.