Ammonium iron(III) citrate (Ammonium ferric citrate) 是一种非运铁蛋白结合的铁的生理形式，会引起的细胞内铁超负荷从而导致细胞铁死亡 (ferroptosis)。Ammonium iron(III) citrate 可以增强蛋白质的产生。
货号:ajcx32658
CAS:1185-57-5
分子式:C6H8O7.xFe.xH3N
分子量：244.62
溶解度:H2O : 33.33 mg/mL |DMSO :< 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2].

Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter[1]. Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L[2].

参考文献:
[1]. Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.
[2]. Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625.