JAG-1, scrambled (scJag-1) TFA 是 JAG-1 (Jagged-1 蛋白) 的杂乱序列。JAG-1, scrambled TFA 与 JAG-1 活性片段具有相同的氨基酸组成，但排列顺序是随机打乱的。JAG-1, scrambled TFA 常用作阴性对照。
货号:ajcx36296
CAS:N/A
分子式:C95H128F3N25O28S3
分子量：2221.37
溶解度:H2O : 10 mg/mL (4.50 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control[1].

In contrast to JAG-1, pretreatment of human pulmonary arterial smooth muscle cells (PASMC) with 50 μM scJag-1 TFA for 30 min has no effect on the transient and plateau components of store-operated Ca2+ entry (SOCE) in comparison to the cells treated with vehicle used to dissolve scJag-1[1].

[1]. Yamamura H, et al. Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol. 2014 May 1;306(9):C871-8.