ElacestrantSenantiomer是elacestrant的低活性对映体。Elacestrant(RAD1901)是有选择性和口服活性的雌激素受体(ER)的降解剂，对ERα和ERβ的IC50值分别为48和870nM。
货号:ajcx13322
CAS:N/A
分子式:C30H38N2O2
分子量：458.63
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Elacestrant S enantiomer is an low activity enantiomer of elacestrant. Elacestrant (RAD1901) is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.

[1]. Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56.