| 规格: | 98% |
| 分子量: | 340.4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
Background:
VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively).1It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 .
1.Poulsen, A., Nagaraj, H., Lee, A., et al.Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602J. Chem. Inf. Model54(11)3238-3250(2014)
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