Tofacitinib metabolite-1 是 Tofacitinib 的代谢物, JAK 抑制剂。Tofacitinib metabolite-1 可用于 Tofacitinib 的药动力学和代谢研究。
货号:ajcx29740
CAS:1640971-51-2
分子式:C16H20N6O2
分子量：328.37
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tofacitinib metabolite-1 is a metabolite of Tofacitinib , a JAK inhibitor. Tofacitinib metabolite-1 can be used in the pharmacokinetics and metabolism studies of tofacitinib[1][2].

[1]. Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73. [2]. Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.