Angiotensinogen (1-14), also known as tetradecapeptide (TDP), is a synthetic peptide precursor of angiotensin I that corresponds to amino acids 1-14 of endogenous human angiotensinogen.
货号:ajcx18104
CAS:N/A
分子式:C83H122N24O19•XCF3COOH
分子量：1760
溶解度:Formic Acid: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Angiotensinogen (1-14), also known as tetradecapeptide (TDP), is a synthetic peptide precursor of angiotensin I that corresponds to amino acids 1-14 of endogenous human angiotensinogen. Angiotensinogen (1-14) is cleaved by renin at the Leu-Val peptide bond to release angiotensin I, which is then converted to angiotensin II by angiotensin converting enzyme (ACE) and exerts vasoconstrictive properties. Angiotensinogen (1-14) (0.001-1 μM) induces contraction of isolated rat femoral resistance vessels, an effect that is reduced by the angiotensin II receptor partial antagonist saralasin and enhanced by the serine protease kallikrein.