(Rac)-JBJ-04-125-02是JBJ-04-125-02的消旋体，JBJ-04-125-02是一种有效的，选择性突变，变构和口服活性的EGFR抑制剂，对EGFRL858R/T790M的IC50为0.26nM。
货号:ajcx29828
CAS:2140807-05-0
分子式:C29H26FN5O3S
分子量：543.61
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M[1].

[1]. To C, et al. Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov. 2019 Jul;9(7):926-943.