8-Gingerol来源于姜的根状茎(Z.officinale)，具有口服活性，可激活TRPV1，EC50值为5.0µM。8-Gingerol抑制COX-2，还能抑制体外H.pylori的生长。
货号:ajcx30080
CAS:23513-08-8
分子式:C19H30O4
分子量：322.44
溶解度:DMSO: ≥ 100 mg/mL (310.14 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].

[1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002). [2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005).