Doxorubicin-SMCC 是抗体偶联药物 ADC 的一部分 (drug-linker conjugate for ADC)。Doxorubicin-SMCC 包含不可降解的 ADC linker 和 DNA 拓扑异构酶 II 抑制剂 Doxorubicin。
货号:ajcx33120
CAS:400647-59-8
分子式:C39H42N2O14
分子量：762.76
溶解度:DMSO : 62.5 mg/mL (81.94 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Doxorubicin-SMCC is a drug-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.