Boc-Val-Cit-PAB-PNP 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
货号:ajcx34252
CAS:870487-10-8
分子式:C30H40N6O10
分子量：644.67
溶解度:DMSO : 250 mg/mL (387.80 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.