Vindesine sulfate 是一种有效的 tubulin 抑制剂，Ki 为 0.110 ?M。Vindesine sulfate 在体外显示出抗增殖作用。Vindesine sulfate 在体内显示出抗肿瘤作用。
货号:ajcx38548
CAS:59917-39-4
分子式:C43H57N5O11S
分子量：852
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo[1].

Vindesine sulfate inhibits L-cells growth and shows about 25% inhibition at 40 nM[1].

[1]. Jordan MA, et al. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 1985 Jun;45(6):2741-7.