规格: | 98% |
分子量: | 1296.5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Background:
Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II by angiotensin-converting enzyme (ACE). It binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM) and increases renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM). In vivo, angiotensin I (5 μg/kg, i.c.v.) increases mean arterial pressure (MAP) and plasma arginine vasopressin (AVP) level in fetal ewes.