A mixture of hydroxy fatty acid-containing ceramides
货号:ajcx22058
CAS:N/A
分子式:C36H71NO4 (for 2-hydroxy stearoyl)
分子量：0
溶解度:Chloroform:Methanol (2:1): Soluble,Methanol: Soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through thede novosynthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.¹This product contains a mixture of hydroxy fatty acid-containing ceramides. [Matreya, LLC. Catalog No. 1323]

1.Ogretmen, B., Pettus, B.J., Rossi, M.J., et al.Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A547 human lung adenocarcinoma cell lineJ. Biol. Chem.277(15)12960-12969(2002)