Background:

Nanangenine C is a drimane sesquiterpene that has been found inAspergillus.¹It is active againstB. subtilis(IC₅₀= 5.7 µg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC₅₀= 4.1 µg/ml).

1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019)