包装: | 5mg |
规格: | 98% |
市场价: | 4249元 |
分子量: | 618.55 |
Background:
Potent p300/CBP inhibitor. Inhibits p300-mediated H3K9 acetylation (IC50 = 33 nM). Inhibits cytotoxicity of DUX4 and overexpression of DUX4 target genes in vitro. Also impairs DUX4-mediated transcription in an animal model of facioscapulohumeral muscular dystrophy (FSHD).