规格: | 98% |
分子量: | 183.2 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
1g | 电议 |
Background:
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc )[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker)[1].
[1]. Finniss, M. C., et al. A versatile acid-labile linker for antibody-drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.