O-DesmethylPKC412-d5(CGP62221-d5)是O-DesmethylPKC412的氘代物。O-DesmethylMidostaurin(CGP62221;O-DesmethylPKC412)是Midostaurin的活性代谢物，通过细胞色素P450肝酶代谢产生，可以作为Midostaurin在体内代谢的指标之一。
货号:ajcx31228
CAS:N/A
分子式:C34H23D5N4O4
分子量：561.64
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

O-Desmethyl PKC412-d5 (CGP62221-d5) is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism[1].

[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83.