规格: | 98% |
分子量: | 512 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Background:
GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1].
Endogenous ligands of GPR34, a G protein-coupled receptor, act on histamine-releasing activity on antigen- or concanavalin A-stimulated rat mast cells and synergize with nerve growth factor on rat mast cells. It is a lipid such as lysophosphatidylserine having the activity of releasing histamine. GPR34 antagonists can be used, for example, for histamine release inhibitors, immune diseases, edema, hyperacidity, etc[1].
[1]. Fumio Ito, et al. Agent for controlling function of gpr34 receptor. WO2006088246 A1.