bis-PEG2-endo-BCN 是一种可降解 (cleavable) 的含 2 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
货号:ajcx32970
CAS:1476737-97-9
分子式:C28H40N2O6
分子量：500.63
溶解度:DMSO : 100 mg/mL (199.75 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.