1,3-Dimethyluracil是由尿嘧啶衍生而来的嘧啶。1,3-Dimethyluracil偶见于人尿中。1,3-Dimethyluracil对hCAI和hCAII有抑制活性，Ki分别为316.2μM和166.4μM。
货号:ajcx29870
CAS:874-14-6
分子式:C6H8N2O2
分子量：140.14
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].

[1]. Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Front Aging Neurosci. 2018 Mar 5;10:51. [2]. GÜney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3261-3.