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ChX710
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ChX710图片
规格:98%
分子量:323.39
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
ChX710可以启动I型干扰素对胞质DNA的反应,诱导ISRE启动子序列、特异性细胞干扰素刺激基因(ISGs)和干扰素调节因子(IRF)3的磷酸化。
货号:ajcx13384
CAS:N/A
分子式:C18H21N5O
分子量:323.39
溶解度:DMSO : 20 mg/mL (61.84 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

ChX710 treatment is found to efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels [1].


[1]. Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7(1):2561.