NH2-PEG6-CH2CH2COOH 是一种可降解 (cleavable) 的 6 单元 PEG 类 ADC linker，用于抗体偶联药物 (ADC) 的合成。NH2-PEG6-CH2CH2COOH 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。
货号:ajcx33194
CAS:905954-28-1
分子式:C15H31NO8
分子量：353.41
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.