| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 2948元 |
| 分子量: | 1153.3 |
Background:
Histone H2AX (134-143) is a C-terminal peptide fragment of histone H2AX that corresponds to amino acid residues 134-143 of the human histone H2AX sequence. Histone H2AX (134-143) is an evolutionarily conserved motif that differentiates histone H2AX from other H2A histones.1 It contains a serine residue that is rapidly phosphorylated upon introduction of DNA double-strand breaks and initiation of DNA fragmentation during apoptosis.
|1. Rogakou, E.P., Nieves-Neira, W., Boon, C., et al. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J. Biol. Chem. 275(13), 9390-9395 (2000).
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