An internal standard for the quantification of cotinine
货号:ajcx20862
CAS:110952-70-0
分子式:C10H9D3N2O
分子量：179.2
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(±)-Cotinine-d₃is intended for use as an internal standard for the quantification of cotinine by GC- or LC-MS. Cotinine is an alkaloid found in tobacco and a major metabolite of nicotine .^1,2It is formed by oxidation of nicotine by the cytochrome P450 (CYP) isoform CYP2A6.²

1.StÅlhandske, T.The metabolism of nicotine and cotinine by a mouse liver preparationActa. Physiol. Scand.78(2)236-248(1970) 2.Murphy, S.E., Link, C.A., Jensen, J., et al.A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokersCancer Epidemiology, Biomarkers & Prevention13(10)1617-1623(2004)