规格: | 98% |
分子量: | 293.4 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
MRE11 endonuclease inhibitor. Prevents double-stranded break (DSB) resection. Enhances non-homologous end-joining (NHEJ) and reduces homologous recombination.
Shibata et al (2014) DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol.Cell 53 7 PMID:24316220