M-31850 (M 31850; M31850) is a novel and potent β-Hexosaminidase inhibitor which exhibited activity against the insect β-N-acetyl-D-hexosaminidase of Hex2. It has the potential to be used for osteoarthritis. M-31850 acts as a substrate-competitive and selective inhibitor against human β-N-acetyl hexosaminidase (IC50 = 6.0 & 3.1 μM for hHex A & hHex B, respectively), while exhibiting much reduced potency against Jack Bean or bacterial Hex (IC50 = 280 & >500 μM for JBHex & SpHex, respectively) and little or no activity against SmHex or hOGN.

纯度：≥98%

CAS：281224-40-6