A neuropeptide with diverse biological activities
货号:ajcx23648
CAS:N/A
分子式:C10H8D5N5O
分子量：224.3
溶解度:DMSO: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

trans-Zeatin-d₅is intended for use as an internal standard for the quantification oftrans-zeatin by GC- or LC-MS.trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.^1,2,3,4It binds to the cytokinin receptorArabidopsishistidine kinase 3 (AHK3) with a K_Dvalue of 1.3 nM.³trans-Zeatin increases chlorophyll levels in etiolatedCucumus sativuscotyledons in a concentration-dependent manner.¹It increases callus growth and shoot formation inN. tabacumcalluses when used at concentrations of 5 and 50 µM.²trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.⁴It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.

1.Fletcher, R.A., and McCullagh, D.Cytokinin-induced chlorophyll formation in cucumber cotyledonsPlanta101(1)88-90(1971) 2.Yamada, Y., Sekiya, J., and Koshimizu, K.Cytokinin-induced shoot formationPhytochemistry11(3)1019-1021(1972) 3.Romanov, G.A., Lomin, S.N., and SchmÜlling, T.Biochemical characteristics and ligand-binding properties of Arabidopsis cytokinin receptor AHK3 compared to CRE1/AHK4 as revealed by a direct binding assayJ. Exp. Bot.57(15)4051-4058(2006) 4.Choi, S.J., Jeong, C.-H., Choi, S.-G., et al.Zeatin prevents amyloid β-induced neurotoxicity and scopolamine-induced cognitive deficitsJ. Med. Food12(2)271-277(2009)