Tryptoquivaline D 是烟曲霉的一种真菌代谢物。
货号:ajcx24052
CAS:60676-56-4
分子式:C28H28N4O7
分子量：532.5
溶解度:
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.^1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 µM.¹Tryptoquivaline D (1-100 µM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.²

1.Prata-Sena, M., Ramos, A.A., Buttachon, S., et al.Cytotoxic activity of secondary metabolites from marine-derived fungus Neosartorya siamensis in human cancer cellsPhytother. Res.30(11)1862-1871(2016) 2.Ramos, A.A., Castro-Carvalho , B., Prata-Sena, M., et al.Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin• An in vitro survey unveils interactions against lung cancer cellsEnviron. Toxicol.35(4)507-517(2020)