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SSR 180711 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SSR 180711 hydrochloride图片
规格:98%
分子量:361.66
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
SSR 180711 hydrochloride 是一种具有口服活性、选择性和可逆的 α7 乙酰胆碱烟碱受体 (n-AChRs) 部分激动剂。
货号:ajcx27116
CAS:446031-79-4
分子式:C14H17BrN2O2.HCl
分子量:361.66
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Partial agonist at α7 nAChR. Enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. Increases extracellular dopamine levels in rat prefrontal cortex. Also exhibits antidepressant-like properties.


Jones et al (2014) Effect of α7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats. Psychopharmacology (Berl). 231 673 PMID:24057763 |Pichat et al (2007) SSR180711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia. Neuropsychopharmacology 32 17 PMID:16936709