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Biotin-PEG4-methyltetrazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biotin-PEG4-methyltetrazine图片
规格:98%
分子量:589.71
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Biotin-PEG4-methyltetrazine 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
货号:ajcx29178
CAS:1835759-81-3
分子式:C27H39N7O6S
分子量:589.71
溶解度:DMSO: 50 mg/mL (84.79 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562