Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone, thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. References: Terdale SS, Dagade DH, Patil KJ. Thermodynamic studies of drug-alpha-cyclodextrin interactions in water at 298.15 K: promazine hydrochloride/chlorpromazine hydrochloride + alpha-cyclodextrin + H(2)O systems. J Phys Chem B. 2007 Dec 6;111(48):13645-52. Epub 2007 Nov 8. PubMed PMID: 17988113.

纯度：≥98%

CAS：53-60-1