| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 4415元 |
| 分子量: | 332.4 |
Background:
Naloxone-d5is an analytical reference material intended for use as an internal standard for the quantification of naloxone by GC- or LC-MS. Naloxone is categorized as an opioid antagonist.1Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose.2,3They have also been used in combination with buprenorphine in the treatment of opiate addiction and in pain management.4,5This product is intended for research and forensic applications.
1.Le Bourdonnec, B., Barker, W.M., Belanger, S., et al.Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profilesBioorg. Med. Chem. Lett.18(6)2006-2012(2008) 2.Boyer, E.W.Management of opioid analgesic overdoseN. Engl. J. Med.367(2)146-155(2012) 3.Bowman, S., Eiserman, J., Beletsky, L., et al.Reducing the health consequences of opioid addiction in primary careAm. J. Med.126(7)565-571(2013) 4.Bart, G.Maintenance medication for opiate addiction: The foundation of recoveryJ. Addict. Dis.31(3)207-225(2012) 5.Chen, K.Y., Chen, L., and Mao, J.Buprenorphine-naloxone therapy in pain managementAnesthesiology120(5)1262-1274(2014)
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