Vorolanib (CM082; X-82) 是一种具有口服活性的 VEGFR/PDGFR 抑制剂。Vorolanib 最大限度地降低了毒性，破坏肿瘤的血管生成和肿瘤细胞增殖，并诱导肿瘤细胞死亡。
货号:ajcx14718
CAS:1013920-15-4
分子式:C23H26FN5O3
分子量：439.48
溶解度:DMSO: 27 mg/mL (61.44 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Vorolanib (CM082; X-82) is an orally active, multikinase VEGFR/PDGFR inhibitor. Vorolanib minimizes toxicity, disrupts tumor angiogenesis and tumor cell proliferation, and induces of tumor cell death[1].

[1]. Bendell JC, et al. Phase I, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Vorolanib in Patients with Advanced Solid Tumors. Oncologist. 2019 Apr;24(4):455-e121.