A neuropeptide with diverse biological activities
货号:ajcx23646
CAS:N/A
分子式:C18H21D13O2
分子量：295.5
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 100 mg/ml,Ethanol:PBS (pH 7.2): 0.5 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

trans-Vaccenic acid-d₁₃is intended for use an internal standard for the quantification of trans-vaccenic acid by GC- or LC-MS.trans-Vaccenic acid is an ω-7 fatty acid that has been found in bovine milk fats.¹Dietary administration oftrans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome.²It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched withtrans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions inLdlr^-/-mice.³

1.Santora, J.E., Palmquist, D.L., and Roehrig, K.L.Trans-vaccenic acid is desaturated to conjugated linoleic acid in miceJ. Nutr.130(2)208-215(2000) 2.Jacome-Sosa, M.M., Borthwick, F., Mangat, R., et al.Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndromeJ. Nutr. Biochem.25(7)692-701(2014) 3.Bassett, C.M., Edel, A.L., Patenaude, A.F., et al.Dietary vaccenic acid has antiatherogenic effects in LDLr-/- miceJ. Nutr.140(1)18-24(2010)