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Artemether(SM-224)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Artemether(SM-224)图片
CAS NO:71963-77-4
规格:98%
分子量:298.4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Semi-synthetic derivative of artemisinin
CAS:71963-77-4
分子式:C16H26O5
分子量:298.4
纯度:98%
存储:Store at -20°C

Background:

Artemether is a semi-synthetic derivative of artemisinin (qinghaosu), a naturally occurring peroxide lactone derived from a traditional Chinese herbal remedyArtemisia annuaL., to enhance the solubility and antimalarial activity of its parental compound. Artemether exhibits potent antimalarial and antischistosomal activities against malarial parasites andSchistosoma japonicuminfections. Although it has not been well elucidated, an endoperoxide bridge within the chemical structure of Artemether might be the key characteristic considered to be responsible for its antimalarial and antischistosomal activities, which can be metabolized by malarial or schistosomal parasites, underin vivoconditions, generating detrimental oxygen radicals to attack parasite macromolecules.


Reference


?[1].Xiao Shuhua and Brian A. Catto.? In vitro and in vivo studies of the effect of artemether on Schistosoma mansoni. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 1989, 1557-1562