| CAS NO: | 141446-96-0 |
| 规格: | 98% |
| 分子量: | 512.6 |
| 包装 | 价格(元) |
| 500ug | 电议 |
| 2.5mg | 电议 |
Background:
1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
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