CytoTrace? Orange CMTMR is a rhodamine-based, cell-permeant, vital fluorescent dye that is retained by cells for prolonged periods (>72 hours) and is passed to daughter cells.
CAS：323192-14-9
分子式：C32H28ClN3O4
分子量：554
纯度：98%
存储：Store at -20°C

Background:

CytoTrace? Orange CMTMR is a rhodamine-based, cell-permeant, vital fluorescent dye that is retained by cells for prolonged periods (>72 hours) and is passed to daughter cells. Cells loaded with long-lasting dyes, including CMTMR, are used to follow cell trafficking and cell-to-cell interactions in vivo.[1],[2],[3]They have also been used to estimate the growth of implanted tumor spheroids.[4] CytoTrace? Orange CMTMR displays excitation/emission maxima of 541/565 nm, respectively.

Reference:
[1]. Brooks, A.E.S., Parsamand, T., Kelly, R.W., et al. An improved quantitative method to assess adhesive properties of Trichomonas vaginalis to host vaginal ectocervical cells using flow cytometry. J. Microbiol. Methods 92(1), 73-78 (2013).
[2]. Buehler, C., Dong, C.Y., So, P.T.C., et al. Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy. Biophys J. 79(1), 536-549 (2000).
[3]. Sato, K., Imai, Y., and Irimura, T. Contribution of dermal macrophage trafficking in the sensitization phase of contact hypersensitivity. J. Immunol. 161(12), 6835-6844 (1998).
[4]. Borgstr?m, P., Hillan, K.J., Sriramarao, P., et al. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res. 56(17), 4032-4039 (1996).