Metixenehydrochloridehydrate是一种抗胆碱能、抗帕金森剂，能够有效抑制二苯羟乙酸奎宁酯与毒蕈碱受体(muscarinicreceptor)结合，IC50和Kd值分别为55nM和15nM。
CAS：7081-40-5
分子式：C20H26ClNOS
分子量：363.94
纯度：98%
存储：Store at -20°C

Background:

Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].

Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM[1].

[1]. Syv?lahti EK, et al. Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung. Pharmacol Toxicol. 1988 Feb;62(2):90-4.