您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > NIBR189
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
NIBR189
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NIBR189图片
CAS NO:1599432-08-2
规格:98%
分子量:429.31
包装与价格:
包装价格(元)
10mg电议
50mg电议
500mg电议
1g电议

产品介绍
EBI2 (GPR183) receptor antagonist
CAS:1599432-08-2
分子式:C21H21BrN2O3
分子量:429.31
纯度:98%
存储:Store at -20°C

Background:

NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).IC50 value: 16/11 nM(Binding/Functional IC50) [1]Target: EBI2/GPR183 antagonistNIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.


参考文献:
[1]. Gessier F, et al. Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem. 2014 Apr 24;57(8):3358-68.