Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C.
CAS:144860-69-5
分子式:C37H54O11
分子量:674.8
纯度:98%
存储:Store at -20°C
Background:
Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs = 2.0 and >500 ug/ml at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50 = 1.58 ug/ml) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50 = 2.0 ug/ml for both).